The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
نویسندگان
چکیده
منابع مشابه
The biosynthesis of artemisinin (Qinghaosu) and the phytochemistry of Artemisia annua L. (Qinghao).
The Chinese medicinal plant Artemisia annua L. (Qinghao) is the only known source of the sesquiterpene artemisinin (Qinghaosu), which is used in the treatment of malaria. Artemisinin is a highly oxygenated sesquiterpene, containing a unique 1,2,4-trioxane ring structure, which is responsible for the antimalarial activity of this natural product. The phytochemistry of A. annua is dominated by bo...
متن کاملArtemisia Annua (qinghao): a Pharmacological Review
Artemisia annua L., also known as sweet wormwood, sweet annie, sweet sagewort and annual wormwood (Chinese: qngho), is a common type of wormwood that is native to temperate Asia, but naturalized throughout the world, and that belongs to the family of the Asteraceae. Currently, Artemisia annua is the source for the production of artemisinin and semi-synthetic artemisinin derivatives (including d...
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Jasmonates (JAs) are important signaling molecules in plants and play crucial roles in stress responses, secondary metabolites' regulation, plant growth and development. In this study, the promoter of AaAOC, which was the key gene of jasmonate biosynthetic pathway, had been cloned. GUS staining showed that AaAOC was expressed ubiquitiously in A. annua. AaAOC gene was overexpressed under control...
متن کاملMapping the potential distribution of high artemisinin-yielding Artemisia annua L. (Qinghao) in China with a geographic information system
BACKGROUND Artemisia annua L. is an important source for artemisinin, a potent drug for treating malaria. This study aims to map and predict the potential geographic distribution of A. annua L. in China. METHODS The Geographic Information System for traditional Chinese medicine (TCM-GIS) was developed and used to map the potential geographic distribution of A. annua L. RESULTS Climatic, eda...
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ژورنال
عنوان ژورنال: Molecules
سال: 2010
ISSN: 1420-3049
DOI: 10.3390/molecules15117603